Job Description

6 month contract- potential to convert

San Francisco, CA

Temp Senior Research Associate, Cancer Cell & Systems Biology

The Opportunity:

As a key member of the Biology team, you will:

• Independently conduct key experiments to support new target identification and validation efforts
• Contribute to the development of and perform in vitro and cell-based assays to support identification of tractable chemical matter targeting new oncogenic targets in RAS-driven cancers
• Apply various cellular, molecular, and genetic techniques to characterize and enhance our mechanistic understanding of novel anti-cancer agents
• Maintain cultures of multiple human cancer cell lines simultaneously to support experimental efforts
• Perform various cell-based assays to interrogate effects of inhibitors on signaling pathways
• Perform microplate-based quantitative assays using reagent kits
• Analyze and interpret experimental data, formulate testable hypotheses and propose follow up experiments within project scope, and present results at internal meetings
• Collaborate with team members to generate novel insights into key drivers of RAS-driven cancers

Required Experience, Skills, and Education:

• Bachelor’s degree or Master’s degree in Cell/Molecular Biology, Biochemistry, Biology, Genetics, or related field
• 6+ years of experience in an industry position or academic lab involving cell/tissue culture and cell/molecular biology OR 3-5 years of experience with a Master’s degree
• Demonstrated proficiency with a wide range of cell and molecular biology techniques (e.g., cell line engineering, SDS-PAGE/Western blot, molecular cloning, DNA/RNA preparation, PCR, qPCR, etc.)
• Proficiency with cell/tissue culture, including the ability to maintain multiple human cancer cell lines simultaneously with strong aseptic technique
• Rigorous, detail-oriented, and quantitative experimentalist
• Proven ability to proactively and independently problem solve with minimum guidance
• Highly organized, with excellent record keeping and written/verbal communication skills
• Demonstrated ability to multi-task, prioritize, and complete tasks efficiently to meet project deadlines
• Innovative and adaptable team-player with an eagerness to learn new techniques

Note: This is a lab-based role. Therefore, it is expected that the team member be on-site 5 days per week.

Preferred Skills:

• Demonstrated proficiency with relevant assay readout technologies (e.g., CellTiter-Glo, AlphaLISA, MSD)
• Experience with automation (e.g., robotic liquid handlers, cell seeders, etc.)
• Familiarity with data processing, curve fitting, and visualization tools to analyze small and large datasets (e.g., GraphPad Prism, Genedata Screener, D360, or Spotfire)

pay within this range will be commensurate with level of experience

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